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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TPX2 All Species: 21.82
Human Site: S209 Identified Species: 48
UniProt: Q9ULW0 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9ULW0 NP_036244.2 747 85653 S209 A K Q K F L K S T E E Q E L E
Chimpanzee Pan troglodytes XP_001153533 746 85517 S208 A K Q K V L K S T E E Q E L E
Rhesus Macaque Macaca mulatta XP_001109645 746 85683 S208 I K Q K V L K S T E E Q E L E
Dog Lupus familis XP_850934 748 86144 S210 V R Q K T L K S T E E Q E L E
Cat Felis silvestris
Mouse Mus musculus NP_082385 745 85876 S211 A R E K V L K S T E E Q E I E
Rat Rattus norvegicus NP_001101260 744 85432 S209 A R E K T V K S T E E Q E L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516385 623 69684 L197 P K P N A P K L T Q P R T P S
Chicken Gallus gallus NP_989768 739 85048 A201 M L K R T N M A G K L K S T E
Frog Xenopus laevis NP_001086751 715 81991 H203 E N L K K N E H S M K V A I S
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798362 948 108486 V340 T Q R R S L R V Y N K S S Q S
Poplar Tree Populus trichocarpa XP_002327911 811 91572 S231 L L K P K S Q S Q S S Q V K G
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 97.5 90.3 N.A. 79.2 79.1 N.A. 40.1 57.5 53.8 N.A. N.A. N.A. N.A. N.A. 31.6
Protein Similarity: 100 99.3 98.6 93.9 N.A. 87.6 87.4 N.A. 53 72.5 70 N.A. N.A. N.A. N.A. N.A. 49.4
P-Site Identity: 100 93.3 86.6 80 N.A. 73.3 73.3 N.A. 20 6.6 6.6 N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 93.3 86.6 86.6 N.A. 93.3 93.3 N.A. 33.3 40 33.3 N.A. N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: 20.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 39.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 26.6 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 37 0 0 0 10 0 0 10 0 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 19 0 0 0 10 0 0 55 55 0 55 0 64 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 0 0 0 19 0 % I
% Lys: 0 37 19 64 19 0 64 0 0 10 19 10 0 10 0 % K
% Leu: 10 19 10 0 0 55 0 10 0 0 10 0 0 46 0 % L
% Met: 10 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % M
% Asn: 0 10 0 10 0 19 0 0 0 10 0 0 0 0 0 % N
% Pro: 10 0 10 10 0 10 0 0 0 0 10 0 0 10 0 % P
% Gln: 0 10 37 0 0 0 10 0 10 10 0 64 0 10 0 % Q
% Arg: 0 28 10 19 0 0 10 0 0 0 0 10 0 0 0 % R
% Ser: 0 0 0 0 10 10 0 64 10 10 10 10 19 0 28 % S
% Thr: 10 0 0 0 28 0 0 0 64 0 0 0 10 10 0 % T
% Val: 10 0 0 0 28 10 0 10 0 0 0 10 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _